Malcolm 'Mal' Reynolds
River Tam
Zoë Alleyne Washburne
Hoban 'Wash' Washburne
Inara Serra
Jayne Cobb
Kaywinnet Lee 'Kaylee' Frye
Simon Tam
Shepherd Derrial Book
The Operative
Mr. Universe
Dr. Mathias
Dr. Caron
Mingojerry 'Mingo' Rample
Fantastic "Fanty" Rample
Lenore
Teacher
Lilac Young Tough
Young River Tam
Boy Student
Girl Student
Ensign
Helmsman
Lab Technician
Trade Agent
Young Female Intern
Vault Guard
Lilac Mom
Lilac Son
Fan Dancer
Mining Camp Boy
Alliance Pilot
Black Room Soldier
News Anchor
Slovenly Beaumonde Man
Bartender (uncredited)
Chinese Snake Dancer (uncredited)
Bar Guy (uncredited)
Screaming Reaver (uncredited)
Lab Security (uncredited)
Bar Security (uncredited)